Premier League Predictions: Picks, Odds, Best Bets for Matchday 4

It’s matchday 4 in the Premier League as club football returns following the international break. The weekend’s schedule is packed with exciting fixtures, highlighted by Sunday’s marquee event: the Manchester Derby.

Contents:

  • Bournemouth vs Brighton: Both Teams to Score
  • Bournemouth vs Brighton: Both Teams to Receive 1+ Cards + Adrien Truffert (BOU) 1+ Fouls Committed
  • Fulham vs Leeds United: Fulham Win
  • West Ham vs Tottenham: Over 8.5 Total Shots on Target (SoT)
  • Manchester City vs Manchester United: Erling Haaland (MCI) 2+ Shots on Target (SoT)

Bournemouth vs Brighton: Both Teams to Score

Odds:

  • American: -175
  • Decimal: 1.57
  • Fractional: 4/7

Brighton return from the international break on the back of a 2-1 comeback win against Manchester City, while Bournemouth impressed before the pause with a strong victory over Tottenham in North London. Both teams showed they can compete with the league’s top sides, and their recent results set up an intriguing matchup. Brighton’s win over City highlighted their high, aggressive press, which can disrupt even the most organized teams, while Bournemouth’s performance demonstrated their ability to exploit defensive gaps when opportunities arise.

Brighton’s pressing system, however, carries inherent risks. Their tendency to press with two of their three central midfielders often leaves spaces between midfield and defensive lines, which opponents can exploit. City were able to find these gaps repeatedly, moving the ball between Brighton’s lines, though they struggled to capitalize in the final third. Bournemouth, with their pace and quality in attack, could see similar success by playing through or around Brighton’s press.

Defensively, Brighton maintain a narrow structure, shifting across toward the ball and congesting central channels when possession is not in the middle. Their three central midfielders rotate as needed, and their wingers tuck inside to block access through the center. This disciplined shape makes it difficult for opponents to break them down centrally, but overcommitting to press or moving slowly can create exploitable pockets of space.

Bournemouth’s attack relies heavily on wing play, drawing defenders wide before quickly moving the ball inside to central options. Success for them will depend on choosing the right moments to switch the play and penetrate Brighton’s half-spaces. The battle on the flanks could turn into a game of “who blinks first,” with Brighton trying to prevent central overloads while Bournemouth look to create them. Their only goal against Tottenham came from this exact pattern, illustrating how effective careful wing-to-central transitions can be against Brighton’s structure.

Given the way these two sides match up in style, and their shared strength on the counter-attack, I expect both teams to find the net in this match. Brighton should see more of the ball, looking to play through central areas, while Bournemouth will be ready to strike whenever counter-attacking opportunities present themselves.

Pick: Both Teams to Score

Bournemouth vs Brighton: Both Teams to Receive 1+ Cards + Adrien Truffert (BOU) 1+ Fouls Committed

Odds:

  • American: -133
  • Decimal: 1.75
  • Fractional: 3/4

In both fixtures between these sides last season, each team picked up at least one card. This trend could continue, as Bournemouth and Brighton are currently tied for cards accumulated in the opening three Premier League matches, with eight apiece. Brighton also lead the league in fouls committed, with 47 so far.

For Bournemouth, Adrien Truffert has started the season well, but he faces a tough test against the pace and directness of Yankuba Minteh down his side. Truffert has already committed five fouls across three matches, averaging 1.66 per game.

I am taking both teams to have at least one player booked by the referee and Bournemouth’s Adrien Truffert to commit 1+ foul.

Pick: Both Teams to Receive 1+ Cards + Adrien Truffert (BOU) 1+ Fouls Committed

*pick is voided if player does not start

Fulham vs Leeds United: Fulham Win

Odds:

  • American: +100
  • Decimal: 2.00
  • Fractional: 1/1

Statistical models give Fulham a 57% chance of winning, yet their odds are still even to take the match. Leeds have struggled to start their Premier League campaign, following an opening 1-0 win against Everton with two matches in which they failed to score, facing quality sides in Arsenal and Newcastle. That context is important, as both opponents rank highly in terms of squad strength and defensive ability. Fulham, meanwhile, have yet to record a Premier League win this season and will be looking to secure their first victory on Saturday.

Deadline day saw Fulham bolster their attack with the arrivals of left winger Kevin from Shakhtar Donetsk for £33 million and right winger Samuel Chukwueze on loan from AC Milan. It will be interesting to see how these new attacking options integrate into the side.

Overall, Fulham have the stronger squad and are the better-equipped team for this matchup. With home advantage at Craven Cottage and the backing of analytical models, I’m taking Fulham to claim their first win of the 2025/2026 Premier League season.

Pick: Fulham Win

West Ham vs Tottenham: Over 8.5 Total Shots on Target (SoT)

Odds:

  • American: -139
  • Decimal: 1.72
  • Fractional: 18/25

Tottenham could feature a new attacking look if Xavi Simmons and Randal Kolo Muani take part in the match. The Spurs come into this game after a 1-0 loss to Bournemouth before the international break, a match in which they managed just one shot on target and created very few opportunities. With these refreshed attacking options, Tottenham will be aiming to increase their shot count and improve their accuracy.

Since Graham Potter’s appointment, West Ham have allowed an average of 4.29 shots on target per Premier League match. Through the first three games of this season, that number has risen to 5.00, the highest in the league. Offensively, West Ham have averaged 3.52 shots on target under Potter historically, with the current season seeing an increase to 4.67 through three matches.

With both sides capable of generating chances and playing at a fast pace, Tottenham’s attacking reinforcements could make this an entertaining contest, with opportunities likely at both ends.

Pick: Over 8.5 Total Shots on Target (SoT)

Manchester City vs Manchester United: Erling Haaland (MCI) 2+ Shots on Target (SoT)

Odds:

  • American: -125
  • Decimal: 1.80
  • Fractional: 4/5

This match is intriguing less for who is on the pitch and more for who is missing. For Manchester United, the absences of Matheus Cunha and Mason Mount are significant. Mount has been a vital link-up player, keeping his spot in the lineup ahead of summer arrival Benjamin Šeško, while Cunha’s pace, power, and eye for goal have been central to United’s counter-attacking threat. Losing both removes two key outlets in United’s attack.

Another storyline lies in goal, with both sides likely to start new keepers. Pep Guardiola’s system relies heavily on a goalkeeper comfortable in possession, but while Donnarumma is among the world’s elite shot-stoppers, his build-up play falls short of what City typically demand. With Trafford already struggling in that area this season, City’s ability to initiate their play from the back will be something to watch closely.

Tactically, City should still find opportunities to exploit United through the central areas. Amorim’s 3-4-3 pushes play wide, leaving just two central midfielders, which City can look to overload. With Aït-Nouri and Nunes pushing higher, players like Doku and Bobb can invert inside rather than stay wide, creating even more congestion in midfield. This will likely force United’s defenders to step out of position to cover the overloads. Luke Shaw and Matthijs de Ligt typically take on that responsibility, but with City pulling them forward, space will inevitably open for Erling Haaland to exploit – and he should see plenty of chances as a result. 

United will also be susceptible to quick breaking counter-attacks as they have been so far this season. With limited numbers in the central midfield in both defense and attack, City will be able to counter very fast and direct through the middle.

I’m taking Erling Haaland to have 2+ shots on target in this match. I expect Manchester City to play very direct at times, looking to feed him in behind United’s backline. United’s defenders will inevitably be forced to step up into midfield at points, leaving gaps for Haaland to exploit, and any slow or mistimed rotations could make those openings even more dangerous. On top of that, Haaland is City’s primary aerial threat on corners.

Considering all of this, I’m confident he’ll comfortably reach the two-shots-on-target mark.

Pick: Erling Haaland (MCI) 2+ Shots on Target (SoT)

*pick is voided if player does not start

Disclaimer: The betting picks and analysis shared are for informational purposes only and are not guarantees of outcome or financial advice. Please gamble responsibly and only risk money you are willing to lose.

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